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Patients often focus only on blood sugar, but hidden damage begins silentlyin the heart, kidneys, and blood vessels

These medications help regulate blood sugar and promote weight loss by reducing appetite and slowing gastric emptying

In islet alpha cells, GLP-1(936) led to inhibition of Ca2+ entry via voltage-gated Ca2+ channels sensitive to -agatoxin, with consequential pertussis-toxin-sensitive depletion of the docked pool of secretory granules, effects that were prevented by the glucagon receptor antagonists REMD2.59 and L-168049

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