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The main liver isoform, THR-b, enhances hepatic fatty acid oxidation and lowers steatosis and hyperlipidemia in animal models, whereas THR-a is important in cardiac function
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In clinical trials, patients on semaglutide 2.4mg lost an average of 14.9% of their body weight over 68 weeks
10.1002/med.20142 21 MohsinS.BaniyasM
