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This dysfunction affects not only the endothelial cells of the coronary vessels but more crucially those in the intramyocardial capillaries and endocardium, where they interact directly with adjacent cardiomyocytes [12]

While injection-site irritation is well recognized, clinicians are increasingly observing broader skin changes in patients treated with semaglutide (Ozempic, Wegovy), liraglutide (Victoza, Saxenda), and tirzepatide (Mounjaro, Zepbound)

Daily mean blood glucose was obtained from a 6-point self-monitored blood glucose profile