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Recombinant human GLP-1 inhibits protein kinase C (PKC)-, but increases protein kinase A (PKA), which reduces oxidative stress in both glomeruli and tubules (Yin et al., 2019)

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This class includes semaglutide (Ozempic for diabetes, Wegovy for weight management) and liraglutide (Victoza for diabetes, Saxenda for weight management)