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Phone: (347) 269-4270 Email: [email protected] Website: www.joinem.co Table of Contents Ozempic (Semaglutide Injection) Rybelsus (Semaglutide Tablets) Compound Semaglutide (Injection) Mounjaro (Tirzepatide Injection) Compound Tirzepatide (Injection) Ozempic (Semaglutide Injection) WARNING: RISK OF THYROID C-CELL TUMORS BLACK BOX WARNING: GLP-1s are contra-indicated in individuals with a history of Medullary thyroid carcinoma, a family history of such, or in patients with Multiple endocrine neoplasia syndrome type 2

Neuron 42 , 983991 (2004)

Subsequent STEP trials on diabetic patients (STEP 2), added-on therapy on intensive lifestyles (STEP 3), a study in Asian people (STEP 6), a comparison study with liraglutide (STEP 8), a study in adolescents (STEP TEENS), a study in persons with heart failure with preserved ejection fraction (STEP-HFpEF), and a study assessing cardiovascular outcome (SELECT-Semaglutide Effects on Heart Disease and Stroke in Patients with Overweight or Obesity trial) showed significant benefit of semaglutide for treatment of obesity and cardiovascular diseases [31-37]

According to the official UK Summary of Product Characteristics (SmPC), acne is not listed as a common or recognised adverse effect of Ozempic

doi: 10.3390/biomedicines10081989 33 CarminaELongoRA