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Local application of GLP-1 to the core of the NAc increases the number of neurons expressing the immediate early gene, c-fos, in this region (Dossat et al., 2011)

Patients considering either option should discuss: Long-term expectations Cost considerations Side-effect management Nutrition support Physical activity plans Ongoing monitoring GLP-1 medications work best as part of a broader metabolic health strategy rather than as isolated quick fixes

doi: 10.1016/j.bbadis.2009.08.015
