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doi: 10.1038/ng.482

It is a microbiome-based approach to supporting one of the body most studied metabolic hormones

Conclusions This case highlights the complex interplay of multiple risk factors - including prior abdominal surgery, adhesive disease, cirrhosis with ascites, chronic kidney disease, chronic constipation, polypharmacy with constipating agents, and long-term tirzepatide therapy - in the development of severe small-bowel obstruction

Women with PCOS suffer from infertility and are put on these drugs off-label to get pregnant even though the manufacturer warns against it due to the teratogenic risk being unknown

It'll be interesting to see how this impacts their global supply chain resiliency.
