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Creatine helps preserve lean muscle, support metabolism, and reduce fatigue, making it a valuable complement to GLP-1 therapy for weight management

they actively improve your bodys overall metabolic and cardiovascular performance

Dipeptidyl peptidase 4 inhibitors prevent the inactivation of GLP-1 and GLP-2, leading to elevated levels of GLP-1 and GLP-2 both after meals and during fasting (45)

Despite this mild increase in heart rate, large-scale cardiovascular outcome trials have consistently demonstrated robust major adverse cardiovascular event (MACE) reductions, indicating that this mild tachycardia does not translate to increased cardiovascular risk for most subjects

The primary endpoint was a composite of death from cardiovascular causes, non-fatal MI or non-fatal stroke, with a significant 20% reduction in the semaglutide group versus placebo