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Islets were then selected and transferred into wells of 96-well plates containing 0.2 mL of KRB with 20 mM glucose and various test compounds as indicated and incubated for an additional 60 min

funding acquisition, supervision, writingreview and editing, Y.P

[DOI] [PubMed] [Google Scholar] 66.Promrat K., Kleiner D.E., Niemeier H.M., Jackvony E., Kearns M., Wands J.R., Fava J.L., Wing R.R

Published July 22, 2025

A participant who tolerated 4 mg well might have done equally well on 8 mg if given the chance, but the rigid escalation plan did not allow such flexibility
