semaglutide major side effects Ozempic and GLP-1 Drugs: Risk of Severe Patel it Like it is:

Expert insights included.

Serena Williams used GLP-1 medication to lose 31 pounds after facing postpartum weight challenges, saying she now feels healthier and more energetic

Early studies suggest GLP-1 drugs like Ozempic may reduce cravings for alcohol and other addictive substances.

Diabetic ketoacidosis (DKA) presents a severe complication of diabetes mellitus (DM), characterized by elevated blood sugar levels, metabolic acidosis, and ketosis

Reduces appetite aids weight loss Common Drugs (Examples) Exenatide Liraglutide Dulaglutide Semaglutide Lixisenatide Clinical Uses Type 2 Diabetes Mellitus (as monotherapy or combination) Obesity / weight management (especially semaglutide, liraglutide) Cardiovascular benefit: reduces major adverse CV events in T2DM with CVD Administration Subcutaneous injection (daily or weekly depending on formulation) Oral semaglutide available for some patients Adverse Effects Gastrointestinal: nausea, vomiting, diarrhea Risk of pancreatitis (rare but serious) Mild hypoglycemia if combined with sulfonylureas or insulin Injection site reactions Contraindications / Precautions Personal/family history of medullary thyroid carcinoma History of multiple endocrine neoplasia syndrome type 2 (MEN2) Severe gastrointestinal disease (gastroparesis) GLP-1 agonists = incretin mimetics