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The first is to approve your prescription and move forward with a treatment plan

If you take prescription medications or have underlying health conditions, discuss supplements with your doctor before starting GLP-1 treatment

Effect of liraglutide on cardiometabolic profile and on bioelectrical impedance analysis in patients with obesity and metabolic syndrome

Dietary strategies to support GLP-1 treatment include: Prioritising protein intake at each meal to enhance satiety and maintain muscle mass during weight loss Consuming adequate fibre from vegetables, fruits, and whole grains to support digestive health and blood glucose stability Eating small portions with regular, structured meals to accommodate slower gastric emptying and minimise gastrointestinal side effects Staying well hydrated , as reduced appetite may inadvertently decrease fluid intake Some patients find that their tolerance for very sweet or high-fat foods diminishes whilst taking GLP-1 medications

As of mid-2025, retatrutide has not received marketing authorisation from the MHRA or EMA and is not available through the NHS or licensed private prescribers