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[DOI] [PMC free article] [PubMed] [Google Scholar] 58.Bkdal TA, Donsmark M, Hartoft-Nielsen ML, Sndergaard FL, Connor A
Some individuals may experience temporary sleep disruption, while others notice improved sleep as they lose weight and their metabolic health improves
The speed of regain depends on how strictly you continue healthy habits, your baseline metabolism, and your genetic predisposition to weight gainparticularly FTO and MC4R variants that influence metabolic rate and fat storage
A 2024 News Medical review notes that berberine activates the AMPK pathway, supporting metabolism, though its effects are milder than GLP-1 drugs like Ozempic
As you lose weight, you risk losing muscle along with fat
