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5 The annual incidence ranges from 8.8 to 23.1 per 100,000 person-years in North America, 0.624.3 per 100,000 person-years in Europe, and 7.317.4 per 100,000 person-years in Oceania, with a prevalence in adults in their 30 s and 40 s

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In the Phase 3 TRIUMPH-4 trial, participants on the 12 mg dose lost an average of 28.7% of their body weight about 71 pounds over 68 weeks

This strategy involves administering smaller-than-standard doses to harness the metabolic and protective benefits of GLP-1 activation while minimizing side effects, cost, and rapid weight loss