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Strengths The most powerful GLP-1 medication studied to date

The right way to understand it is as a next-generation amylin analogue with promising clinical data, unresolved regulatory status, and clear differences from semaglutide, tirzepatide, and retatrutide

Prez-Pevida B, Escalada J, Miras AD, Frhbeck G (2019) Mechanisms underlying type 2 diabetes remission after metabolic surgery

Therefore, it should only be used during pregnancy if the potential benefit justifies the potential risk to the fetus

[7] Two trials in the phase 3 TRIUMPH program reached primary completion in April 2026: TRIUMPH-1, a master protocol in adults with obesity or overweight, and TRIUMPH-3, in participants with severe obesity and established cardiovascular disease