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A Research Study Investigating Semaglutide in People With Early Alzheimers Disease (EVOKE) ClinicalTrials.gov Identifier: NCT04777396

En ese caso, la indicacin fue mejorar el control glucmico en pacientes mayores de 10 aos y reducir el riesgo cardiovascular en adultos con diabetes tipo 2 y enfermedad cardaca establecida

Other research highlights: 30% of GLP-1 users tested positive for SIBO or IMO even after accounting for diabetes (5) GLP-1 medicines caused microbiome changes and altered metabolism in mice (6) GLP-1 medicines tested in humans only had noticeable microbiome changes by 48 weeks (7) Despite not necessarily having slower gut motility, one study found that 88.9% of obese patients had SIBO (8) A meta analysis of people with IBS symptoms, found that up to 78% of people had SIBO, many of whom were undiagnosed (9) Overall, Sun and colleagues (1) could not prove a mechanistic link between GLP-1 medications and SIBO, however they did find that SIBO was twice as likely in GLP-1 users

Hydration and Timing Strategies for Faster Relief Drink 2.53 liters of water daily, distributed throughout the day in 250350 mL intervals

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