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The BSA provides albumin binding sites complexing the C18 fatty diacid chain, maintaining Semaglutide in the albumin-bound soluble form that constitutes its pharmacokinetically relevant circulating species and preventing surface adsorption losses and micelle aggregation at sub-micromolar working concentrations

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The impact of hemodialysis on dapagliflozin exposure is not known [see DOSAGE AND ADMINISTRATION , WARNINGS AND PRECAUTIONS , Use In Specific Populations and Clinical Studies ]