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On April 30, 2026, the FDA took the more sweeping step of proposing to permanently exclude semaglutide, tirzepatide and liraglutide from the 503B Bulks List the list of ingredients that large-scale compounding facilities are legally permitted to use

However, current clinical evidence does not support this transition

Mozaffarian reports research funding from the National Institutes of Health, Kaiser Permanente Fund at the East Bay Community Foundation, National Association of Chain Drug Stores Foundation, Google Health, and The Rockefeller Foundation

doi:10.1007/s00125-008-1149-y Buteau J

Hepatology 2018;67:328-357
