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doi: 10.1056/NEJMoa1812389 10 NealBPerkovicVMahaffeyKWde ZeeuwDFulcherGEronduNet al

Not only does obesity have direct medical implications, it is also associated with an increased risk of a variety of other conditions termed obesity related complications (ORCs), such as Type II diabetes mellitus (T2DM), cardiovascular disease (CVD), osteoarthritis, sleep apnoea and certain types of cancers [2]

Whats it like to come off a GLP-1

For example, Wegovy (semaglutide) was approved for chronic weight management by the FDA in 2021

The administration of AdPLA2 siRNAs by MP promoted a reduction of AdPLA2 expression levels (50%) but was too strong for the one obtained by injection (70%)