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Pregnancy safety recommendations for compounded versions: The same general washout timeline appliesstop at least 2 months before planned conception for semaglutide-based compounds, and follow similar timing for tirzepatide-based compounds

Those with liver disease, kidney impairment, or multiple concurrent medications require special attention due to increased interaction risk and altered drug clearance

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Methylglyoxal (MG) is one kind of intracellularly formed -ketoaldehydes, which are essential sources of intracellular AGEs

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