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A large-scale genome-wide association study published in Nature in April 2026, conducted by 23andMe researchers using data from 27,885 GLP-1 medication users, identified a specific variant in the GLP1R gene the gene that encodes the primary receptor these drugs target associated with differential weight loss efficacy

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Tirzepatide: Even greater, with average weight loss of 15-22% depending on dose

Labs can also help providers and patients track their results and see the impact of GLP-1 receptor agonist treatmentnot just in improving individual lab values, but also in reducing their overall risk of a major adverse event

Mounjaro Dosage and Administration In the context of dosage, Mounjaro is administered as a subcutaneous injection weekly, providing a consistent approach towards glucose regulation