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Other GLP-1R populations in the ACB, LSc, PVH, lateral hypothalamus (LHA), and VTA are involved in food choice, reward, and taste aversion (2125)

This is consistent with anecdotal reports showing the increase in semaglutide ADM use being larger in some metropolitan cities than others, and does not always correlate with high diabetes prevalence (Trilliant Health, 2023)

Clarke and colleagues similarly noted that the majority of patients tolerated GLP-1RA therapy without requiring treatment cessation due to IBD-specific complications (96)

(30,31) Both studies provided compelling evidence that semaglutide use is associated with reduced rates of prosthetic joint infections, sepsis, and hospital readmissions