glp-1 mimetics Clinical Focus on Agonists in Type 2 Diabetes Mellitus Possible mechanisms of action of

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Your body has built tolerance

Keywords Obesity GLP-1RA Eating disorder Atypical anorexia nervosa Bulimia nervosa Binge-eating disorder Cognitive behavior therapy Treatment Introduction Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are a class of drugs initially approved for the treatment of type 2 diabetes

In a small RCT of Alzheimers disease, liraglutide improved cognitive function and brain volume over one year (Edison P et al, Alzheimers & Dementia 2021;17(Suppl 9):e057848)

This multicenter, double-blind, placebo-controlled trial enrolled people with NAFLD with liver fat content at or above 10% by MRI-PDFF, a FibroScan liver stiffness measure below 10 kPa, alanine aminotransferase (ALT) at or below 75 IU/L, and no diabetes or non-insulin-dependent diabetes with A1C below 9.5%