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That leaves open questions about long-term and real-world risks

Common signs of GLP-1-related body skin changes include: Sagging skin on the upper arms, abdomen, inner thighs, and under the chin Crepey texture a thin, tissue-paper-like appearance, most noticeable on the arms, chest, and knees Rough, uneven texture as skin loses hydration and the outer skin barrier weakens Dullness due to reduced circulation, moisture, and cellular turnover Skin laxity skin that feels loose or less supported as fat volume decreases These changes are not permanent or inevitable and with the right approach, you can meaningfully support your skin's ability to adapt, visibly improving firmness, texture, and hydration over time

Others will require a new prescription

If they fail in this duty, they should be held accountable for the harm they cause

Some patients increase exercise as part of their weight management program, potentially leading to muscle fatigue and cramping if hydration and electrolyte replacement are inadequate