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If youre concerned about digestive side effects or have a history of gastrointestinal issues, discuss these with your doctor before starting treatment

The nutrients support energy, metabolism, and cardiovascular healthneeds we all share during weight loss

Freemark M, Bursey D

In individuals with T2DM, chronic hyperglycemia is known to downregulate GIPR expression and impair GIP-stimulated insulinotropic activity, thereby limiting the efficacy of GIP monotherapy [21]

For example, in several clinical studies, between 33% and 57% patients treated with exenatide [141] and between 24% and 76% of patients treated with lixisenatide [53, 134, 142-148] reported nausea