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While weight loss effects can vary depending on the drug, studies show that all GLP-1 meds can result in an average weight loss of about 10.5 to 15.8 []

Angela Fitch, knownwell chief medical officer and Obesity Medicine Association president, joins 'Squawk Box' to discuss potential mental health side effects of GLP-1s, how these concerns might affect the market, why patients may choose to stop taking GLP-1s, and more.

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Among these effects, increased insulin sensitivity, either by direct action on target organs or secondary to weight loss, might act synergistically with enhanced beta-cell function and insulin upregulation in the pancreas, collectively improving metabolic control.