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Phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptor-Gs complex

Patients with binge eating disorder who start a GLP-1 should initiate therapy at a low dose and titrate slowly

Gastroenterology 144 , 580590.e7 (2013)

it increases the risk of numerous health problems, including heart disease, high cholesterol, high blood pressure, diabetes, liver disease, sleep apnea, and some forms of cancer

While the buttocks have adequate subcutaneous tissue, the difficulty of self-injection in this area and the lack of clinical data supporting this site mean it is not recommended
