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Smaller, observational clinical experiences and case reports suggest some patients may tolerate concurrent use, but these anecdotal accounts cannot substitute for rigorous trial data

The weekly dosing schedule improves convenience and cardiovascular outcome trials have demonstrated significant reductions in major adverse cardiac events among high risk patients

Having 24/7 access to a dedicated team means that if you are ever confused about your dosing schedule or what to do after a missed dose, you have an expert to turn to immediately

GLP-1R expressing cells are widely expressed in mouse and non-human primate brain (Heppner et al., 2015)

RAF Scores: HCC 18 0.302 HCC 19 0.105 MEAT Criteria Element Example Monitor Blood glucose levels, A1C, weight, foot exam, eye exam Evaluate Review of A1C results, renal function, or symptoms Assess Type 2 DM uncontrolled with A1C 8.9%, worsening neuropathy Treat Prescribed Metformin, adjusted insulin dose, dietary counseling TAMPER Criteria Component Example T Treatment Oral hypoglycemics, insulin therapy A Assessment A1C 8.9%, not at goal M Monitor Follow-up labs, blood sugar log P Plan Recheck A1C in 3 months