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Realistic expectations are crucial when considering tirzepatide or other GLP-1 receptor agonists

This condition is more common in older adults, in part because levels of hormones that help protect muscle including sex hormones, growth hormone, and related growth factors tend to decline with age, says Michael Schwartz, MD, a researcher and professor of medicine, metabolism, endocrinology, and nutrition at UW Medicine in Seattle

No other participants reported vomiting

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51 One significant challenge is the high rate of gastrointestinal adverse events associated with these compounds, which may be related to their pharmacokinetic properties and direct gastrointestinal irritation