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Requirements may include documentation of medical necessity, including BMI and comorbid conditions, proof or statement of a trial of lifestyle modification, or documentation that other medications were ineffective or contraindicated. That is also true of Aetnas prior authorization policy for Qsymia, which imposes quantity limits because phentermine is a controlled substance

Figure 1, MASLD and cardiometabolic HFpEF may therefore be understood as interconnected manifestations of shared metabolic stress, inflammation, and fibrosis-related remodeling

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