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Aging is characterized by a progressive decline in physiological function, an increased risk of chronic diseases, and multiple molecular and cellular alterations, including inflammation, oxidative stress, and mitochondrial dysfunction

UChicago Medicine bariatric surgeon Vanessa Buie, MD, MBA, explains the benefits of surgery as a long-term alternative to taking GLP-1 medications

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These delays highlight the structural barriers that can slow adoption in populations with higher rates of comorbidities

The high prevalence of comorbidities such as diabetes, visceral obesity, and aging, which contribute to systemic inflammation, plays a pivotal role in the pathogenesis and progression of HFpEF