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Description
Primarily triggered by food consumption, GLP-1 release occurs 10 15 minutes after eating

Individuals with type 2 diabetes, particularly those on multiple medications, require dose adjustments and enhanced monitoring once tirzepatide therapy begins

Not as an independent driver of weight loss the evidence for that is weak
Improves Insulin Sensitivity & Reduces Inflammation Insulin resistance and chronic inflammation are key contributors to cardiovascular disease

Details of the LC gradient and ionization parameters are provided in Supplementary Table S3