glp-1 drugs heart failure The effect of receptor agonists on cardiac remodeling in patients with preserved and reduced ejection fraction: a systematic review and meta-analysis | Heart Failure Reviews Effects of GLP-1 Receptor Agonists

GLP-1 and its synthetic analogs have emerged as significant therapeutic agents for the management of metabolic disorders, merging glycemic control with weight loss through innovative structural and delivery breakthroughs

Therefore, there is a need to identify those potential changes and adjust patients medication doses in order to achieve higher efficacy and avoid toxicity.

For example, semaglutide and empagliflozin showed no significant difference in 3-point MACE (HR 1.05

Adverse psychiatric effects associated with GLP-1 RAs, including depression, anxiety, and suicidal ideation, are noted in pharmacovigilance analyses, with variations among different GLP-1 RAs

88% reduced sugar cravings