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For example, recent studies have reported clinical benefits in patients with heart and kidney failure

The firm has not published data beyond the press release, but it appears that those who take GLP-1s have much higher costs in the first year, and their inflation rate in year two is lower than those not on GLP-1s

PLoS One 6 (9), e25269

As such, therapy in low-risk individuals should be guided by treatment effects on metabolic outcomes, such as HbA 1c reduction and weight loss, rather than cardiovascular outcomes