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Safeguarding CAR-T therapy: Addressing clinical safety concerns and mitigation strategies Although combination therapies can markedly enhance antitumor efficacy, they also increase the risk of systemic toxicities, most notably CRS and immune effector cell-associated neurotoxicity syndrome (ICANS), as well as on-target, off-tumor damage

Tirzepatide mimics the GIP pathway in addition to the GLP-1 pathway

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Mioduchoski, FNP-BC If youre still early in treatment, our guide on tirzepatide 2.5 mg weight-loss expectations explains what many patients experience during the starting phase of therapy

doi: 10.1038/aps.2011.149