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While the potential to restore beta-cell function is possible in early disease states, effective therapies and useful markers for gauging effectiveness of treatments are not known. Marian Yurchishin, MS At the studys conclusion, researchers found that while study participants both lost weight following either the keto or low-fat diet, those following keto experienced a decrease in the proportion of proinsulin secreted to a greater extent, a change that was associated with an improvement in beta-cell function

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If tirzepatide was used primarily for weight reduction or glycemic control, the observed benefits on COPD outcomes may have been mediated largely through improvements in metabolic status rather than direct pulmonary effects