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Dawkins says, Since the GIP [glucose-dependent insulinotropic polypeptide] hormone acts as an antiemetic, the dual agonist tirzepitide is associated with fewer adverse side effects and better tolerance. References 1
Treatment of HFpEF beyond the SGLT2-Is: Does the addition of GLP-1 RA improve cardiometabolic risk and outcomes in diabetic patients

FDA Resolves Semaglutide Shortage: What This Means for GLP-1 Compounding Pharmacies and Telehealth Weight Loss Companies On February 21, 2025 , the FDA officially determined that the shortage of semaglutide injection products has been resolved

Because these GLP-1s have been available for only a few years, we don't yet know if long-term use will reveal additional adverse effects

Peptide-oligourea hybrids analogue of GLP-1 with improved action in vivo
