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Description
Cooper, D
6.1 Insulin therapy Absolute insulin deficiency is the main characteristic of PDM that makes insulin replacement the foundation of its treatment ( 6.1.1 Principles of insulin therapy The most flexible option from a physiological point of view is the basal-bolus regimen, which comprises basal insulins of long-acting formulations such as glargine and degludec, and rapid-acting insulins at meal-time
Circulating glucagon-like peptide-1 (GLP-1) inhibits eating in male rats by acting in the hindbrain and without inducing avoidance

48.Monti G., Gomes Moreira D., Richner M., Mutsaers H

Typical clinical doses range from about 1,000 to 1,500 mg per day divided across meals
