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While there is limited evidence regarding tirzepatide use specifically in patients with significant thyroid disease (as these patients were typically excluded from pivotal trials), there is no established direct pharmacological interaction between tirzepatide and Graves disease pathophysiology

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Bei wchentlicher Anwendung erzielte Survodutid bei bergewichtigen oder adipsen Personen ber einen Zeitraum von 46 Wochen eine signifikante Gewichtsabnahme von bis zu 18,7 %