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Metabolic Powerhouses: GLP-1 RAs and SGLT2 Inhibitors GLP-1 Receptor Agonists (GLP-1 RA) The Brain-Gut Connection Mechanism: Mimics the natural incretin hormone GLP-1 to regulate metabolism and appetite

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Neuroprotective Effects of GLP-1 Receptor Agonists in Neurodegenerative Disorders: A Large-Scale Propensity-Matched Cohort Study
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In terms of kidney function, while the initial eGFR for GLP-1 RAs users was notably lower, the difference was no longer significant by the D60-90 interval, hinting at a possible stabilization or amelioration in kidney function attributed to GLP-1 RAs therapy (Figure S2)
