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Results Semaglutide 2.4 mg had higher treatment costs (3285.55) compared with liraglutide 3 mg (2742.47) but demonstrated greater efficacy and a lower cost of control across all weight loss targets

This study shows that the insulinotropic actions of the dual GIPR and GLP-1R agonist, tirzepatide, depend on GIPR, and that tirzepatide has weaker activity at the mouse GIPR than murine GIP.