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In addition, studies have found that IFN- released by immunotherapy-activated CD8 + T cells and radiotherapy-activated macrophages can independently and synergistically inhibit SLC7A11.This leads to a decrease in cystine uptake, which in turn increases lipid peroxidation and ferroptosis, making tumor cells sensitive to radiotherapy (263)

[DOI] [PubMed] [Google Scholar] 108.Packer M, Zile MR, Kramer CM, et al

Researchers proceeding despite these unknowns must accept that they are operating without the safety data that clinical trials are designed to generate
doi: 10.1166/jbn.2017.2474 [DOI] [PubMed] [Google Scholar] 28.Waghule T, Singhvi G, Dubey SK, et al

La aprobacin de hoy es otra muestra de lo que la FDA puede lograr cuando nos atrevemos a hacer cosas nuevas y audaces
