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Among these changes, a significant decrease in Akkermansia muciniphila was reported

Physiol Rep 5(7):e13250 Musso C, Cochran E, Moran SA et al (2004) Clinical course of genetic diseases of the insulin receptor (type A and Rabson-Mendenhall syndromes): a 30-year prospective

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They also enhance metabolism and reduce cravings, supporting long-term weight loss

Thus, exenatide treated patients maintained their cognitive benefit 12-months following drug cessation, however, it should be noted that cognitive scores also remained unchanged for controls between 12 and 24 months