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In 2024, there were 8.4 million prescriptions and $8.6 billion in spending on GLP-1s in Medicaid, and 21.8 million claims and $27.5 billion in gross spending (not excluding rebates) on GLP-1s in Medicare (Figure 1)

CrossRef Angiotensin II up-regulates sodium-glucose co-transporter 2 expression and SGLT2 inhibitor attenuates Ang II-induced hypertensive renal injury in mice Kana N

One side effect that gets people asking questions: dysesthesia TRIUMPH4 reporting mentions dysesthesia (odd, uncomfortable sensations like tingling/burning) and says it was generally mild and infrequently led to discontinuation

Your body is already adapting to a new medication

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