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New data on Hengrui Pharma and Kailera Therapeutics investigational oral GLP-1 have validated the late-stage weight loss asset and paved the road for a regulatory submission in China, but analysts pointed to high rates of nausea and vomiting that could challenge the ongoing U.S

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When combined with GLP-1 drugs, they may lead to even greater weight loss, making them a promising next step in obesity treatment.