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Graphic abstract Similar content being viewed by others Introduction Depression is a chronic and recurrent mood disorder and one of the major health concerns in modern society, which, according to the World Health Organization (WHO), affects more than 264 million people worldwide

J Int Soc Sports Nutr 10(1):6 [DOI] [PMC free article] [PubMed] [Google Scholar] 53.Li N, Chen S, He Y, Chen Y, Duan X, He W et al (2025) Effects of oral supplementation of beta -hydroxy-beta -methylbutyrate on muscle mass and strength in individuals over the age of 50: a meta-analysis