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Description
GLP-1 Receptors action on brainstem GABA neurons Examining the contribution of nucleus tractus solitarius (NTS) glucagon-like peptide-1 receptors (GLP-1Rs) to the anorectic potential of the FDA-approved obesity drug liraglutide and highlights a phenotypically distinct (GABAergic) population of neurons within the NTS that express the GLP-1R and are involved in the mediation of liraglutide signaling

Food and Drug Administration (FDA) has approved two oral GLP-1 options: Wegovy (semaglutide) and Foundayo (orforglipron)

This group noted there is no evidence to suggest optimal duration of fasting

2012;303(7):F96371

Nausea is the most common side effect of GLP-1 meds like Ozempic and Wegovy and is estimated to affect up to half of people taking these weight loss drugs
