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Previous reviews of clinical trials evaluated the effect of the SGLT-2i and GLP-1RA combination on metabolic factors, and they showed a mostly positive effect [65, 66]
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Moreover, exendin-4 inhibits migration, cell invasion, and colony formation of many cancers, making it a possible treatment for malignant cells, specifically in prostate cancer
Distinct alterations of hypothalamic proteomic profiles by GLP1/E in lean and obese PCOS mice Finally, considering that the hypothalamus is likely the primary target of the GLP1/E conjugate, we assessed changes in global hypothalamic proteome in PWA and PNA mice following GLP1/E treatment, using cutting-edge liquid chromatographytandem mass spectrometry (LC-MS/MS)
doi: 10.1002/jnr.10611 [DOI] [PubMed] [Google Scholar] 153
