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Losartan slows the decrease of kidney function in patients with high blood pressure and type-2 diabetes.

And the clinical results have been impressive

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Semaglutide, a GLP-1 (glucagon-like peptide-1) receptor agonist, is widely prescribed for weight loss in non-diabetic populations
Glucagon-like peptide1 receptor (GLP-1R) agonists have been found to reduce alcohol drinking in rodents and overweight patients with alcohol use disorder (AUD)
