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Acknowledgements We acknowledge the contributions of the clinical staff of the Intramural Research Program of the National Institute on Drug Abuse, and the Clinical Research Unit of Johns Hopkins Bayview Medical Center, as well as the University of Maryland, Baltimore, a member of the Graduate Partnership Program, National Institutes of Health (NIH)

Beyond metabolic disease, excess BW affects almost all of the bodys major organ systemsincluding the endocrine, GI, cardiovascular, renal, and central nervous systems
