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Eli Lilly's new pill starts shipping today, Novo Nordisk's oral Wegovy is three months into its launch, and doctors are already telling us that the way patients think about these drugs is shifting fast.

The anorexigenic peptide glucagon-like peptide-1 (GLP-1) is secreted from gut enteroendocrine cells and brain preproglucagon (PPG) neurons, which respectively define the peripheral and central GLP-1 systems

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